Drug Dissolution of Urinary Stones: Chinese Expert Consensus
Drug dissolution works best for uric acid stones by alkalinizing urine, and can reduce surgery for selected patients.
What Is Drug Dissolution
Drug dissolution uses medicines to change urine properties and dissolve stones, especially uric acid stones. It can reduce the need for surgery.
Who Benefits Most
Uric acid stones respond best, with high complete-dissolution rates. Cystine and infection stones are less suitable; calcium stones are mainly prevented.
Before Treatment
Stone composition analysis is the gold standard. Imaging and metabolic urine tests guide the plan and rule out obstruction or infection.
Key Cautions
Pregnancy, severe obstruction, uncontrolled infection, and poor kidney or liver function are contraindications. Informed consent is required before starting.
During and After
Alkalinizing the urine raises uric acid solubility. Regular follow-up tracks progress and helps prevent new stone formation.
